Query Small Molecule
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Small Moleccule Name List
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Name: paclitaxel
DrugBank ID: DB01229
Structure:
Description: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS brevifolia. It stabilizes microtubules in their polymerized form leading to cell death. [PubChem] ABI-007 (Abraxane) is the latest attempt to improve upon paclitaxel, one of the leading chemotherapy treatments. Both drugs contain the same active agent, but Abraxane is delivered by a nanoparticle technology that binds to albumin, a natural protein, rather than the toxic solvent known as Cremophor. It is thought that delivering paclitaxel with this technology will cause fewer hypersensitivity reactions and possibly lead to greater drug uptake in tumors.
Association:   figure  
Small molecule miRNA P-value Correlation
paclitaxel hsa-miR-15a 0.04593 positive
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