Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

JAK3

Description:

Janus kinase 3 [Source:HGNC Symbol;Acc:6193]

Location:

Chr19:17935589-17958880[-]

CRmiRSNP:

~ Export ~

Records:null

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1 [First] [Prev] [Next] [Last]

Compound:

~ Export ~

Records:590

Gene	Compound	Gen_sig	Exp_pattern
JAK3	NSC 724771	0.027	Down
JAK3	(1S,4R,5R,8R,12R,13S)-1,5-dimethyl-9-methylene-11,14,15,16-t etraoxatetracyclo[10.3.1.04,13.08,13]hexadec-10-yl]oxy}-3-he xenyl)oxy]-1,5,-dimethyl-9-methylene-11,14,15,16-tetraoxatet racyclo[10.3.1.04,13.08,13]hexadecane	0.021	Down
JAK3	2-[(Dimethylamino)-1-ethyl]-5,6-dihydro-2,3-dimethoxy-8,9-me thylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinoline Formic Acid	0.01	Down
JAK3	6-[3-(Bis-hydroxyethylamino)-1-propyl]-5,6-dihydro-2,3-~ dimethoxy-8,9-methylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinoline hydrochloride	0.014	Down
JAK3	6-[(3-Thiazolylamino)-1-propyl]-5,6-dihydro-2,3-dimethoxy-~ 8,9-methylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinoline hydrochloride	0.004	Down
JAK3	2,2'-(1,4-phenylene)bis(1,3-dimethylimidazolidine)	0.006	Down
JAK3	NSC 726260	0.026	Down
JAK3	NSC 726373	0.013	Up
JAK3	Bis-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline) -6-propylamino}ethane Bis(trifluoroacetate	0.036	Down
JAK3	1-(3-diethylarsino-3-thio-2-methyl-1-oxopropyl)-L-proline	0.03	Down
JAK3	1, 1'[Pentane-1,5-diyl)dioxy]bis(11as)-2-fluoro-7-methoxy-1,2,3 ,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one	0.03	Down
JAK3	2-carboxy-(2'-furyl)-7-chloro-3-trifluoromethylquinoxaline 1,4-dioxide	0.035	Down
JAK3	6-(3-Aminopropyl)-5,6-dihydro-8,9-methylenedioxy-5,11-dioxo- 3-nitro-11H-indeno[1,2-c]isoquinoline Hydrochloride Salt	0.001	Down
JAK3	Dasatinib	0.001	Up
JAK3	NSC 732719	0.012	Down

Expression pattern: Sensitivity / Resistance
Total:40 Current:36 First Prev Next Last

SNP:

~ Export ~

Records:150

SNP	Gene	SNP_location	SNP_allele
rs148321247	JAK3	Chr19:17935606	C/G
rs148321247	JAK3	ChrLRG_77:17935606	C/G
rs147498283	JAK3	Chr19:17935621	A/-
rs147498283	JAK3	ChrLRG_77:17935621	A/-
rs11888	JAK3	Chr19:17935626	T/C
rs11888	JAK3	ChrLRG_77:17935626	T/C
rs11547269	JAK3	Chr19:17935627	T/C
rs11547269	JAK3	ChrLRG_77:17935627	T/C
rs76204136	JAK3	Chr19:17935749	C/T
rs76204136	JAK3	ChrLRG_77:17935749	C/T
rs188773566	JAK3	Chr19:17935791	A/T
rs188773566	JAK3	ChrLRG_77:17935791	A/T
rs191522931	JAK3	Chr19:17936004	G/A
rs191522931	JAK3	ChrLRG_77:17936004	G/A
rs145985086	JAK3	Chr19:17936029	G/A

Total:10 Current:1 [First] [Prev] Next Last

miRNA:

~ Export ~

Records:129

Gene	Gen_transcript	miRNA	miR_location
JAK3	ENST00000317306	hsa-mir-10a-5p	Chr17:46657266-46657288[-]
JAK3	ENST00000317306	hsa-mir-127-3p	Chr14:101349372-101349393[+]
JAK3	ENST00000379695	hsa-mir-127-3p	Chr14:101349372-101349393[+]
JAK3	ENST00000361469	hsa-mir-130a-5p	Chr11:57408691-57408712[+]
JAK3	ENST00000222246	hsa-mir-141-3p	Chr12:7073318-7073339[+]
JAK3	ENST00000317306	hsa-mir-141-3p	Chr12:7073318-7073339[+]
JAK3	ENST00000379695	hsa-mir-141-3p	Chr12:7073318-7073339[+]
JAK3	ENST00000379695	hsa-mir-151a-5p	Chr8:141742722-141742742[-]
JAK3	ENST00000317306	hsa-mir-15a-3p	Chr13:50623266-50623287[-]
JAK3	ENST00000361469	hsa-mir-15a-3p	Chr13:50623266-50623287[-]
JAK3	ENST00000379695	hsa-mir-15a-3p	Chr13:50623266-50623287[-]
JAK3	ENST00000317306	hsa-mir-17-3p	Chr13:92002909-92002930[+]
JAK3	ENST00000379695	hsa-mir-17-3p	Chr13:92002909-92002930[+]
JAK3	ENST00000361469	hsa-mir-181a-2-3p	Chr9:127454797-127454818[+]
JAK3	ENST00000222246	hsa-mir-182-5p	Chr7:129410287-129410310[-]

Total:9 Current:1 [First] [Prev] Next Last