Statistics

  • Compound:1164
  • SNP:126757
  • miRNA:319
  • Gene:17625
  • CRmiRSNP:150

Query Gene
Gene name:

Example:  BCL2L11,  ERCC1
Symbol: TOP3A
Description: topoisomerase (DNA) III alpha [Source:HGNC Symbol;Acc:11992]
Location: Chr17:18174742-18218321[-]
CRmiRSNP:

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Records:null
Compound CRmiRSNP SNP_sig Model Molecule Mol_sig Type
Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1  [First] [Prev] [Next] [Last] 
Compound:

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Records:390
Gene Compound Gen_sig Exp_pattern
TOP3A 2,2'-(1,4-phenylene)bis(1,3-dimethylimidazolidine) 0.006 Down
TOP3A NSC 726373 0.004 Up
TOP3A 1-(3-diethylarsino-3-thio-2-methyl-1-oxopropyl)-L-proline 0.039 Down
TOP3A 1, 1'[Pentane-1,5-diyl)dioxy]bis(11as)-2-fluoro-7-methoxy-1,2,3 ,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one 0.033 Down
TOP3A 6-(3-Aminopropyl)-5,6-dihydro-8,9-methylenedioxy-5,11-dioxo- 3-nitro-11H-indeno[1,2-c]isoquinoline Hydrochloride Salt 0.037 Down
TOP3A Dasatinib 0.006 Up
TOP3A NSC 732956 0.023 Down
TOP3A NSC 734201 0.014 Up
TOP3A NSC 734385 0.012 Down
TOP3A NSC 734631 0.001 Down
TOP3A Ethyl 4-[6-(2-furyl)-2-(methylsulfanyl)-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-3-yl]butanoate 0.004 Up
TOP3A 6-(3-Bromopropyl)-5,6-dihydro-9-methyl-3-nitro-5,11-dioxo-11 H-indeno[1,2-c]isoquinoline 0.041 Down
TOP3A 4-[(Z)-2-(5-nitro-2-furyl)ethenyl]-6-(4-phenylpiperazin-1-yl )-1,3,5-triazin-2-ylamine 0.012 Down
TOP3A NSC 736154 0.003 Down
TOP3A 1,2-Dithiolan-3-yl-N-(3'-methoxyestra-1',3',5'(10')-triene-1 7'b-yl)pentanamide 0.025 Down
Expression pattern: Sensitivity / Resistance
Total:26 Current:25  First Prev Next Last 
SNP:

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Records:17
SNP Gene SNP_location SNP_allele
rs181367694 TOP3A Chr17:18177270 A/G
rs117810073 TOP3A Chr17:18177312 G/A
rs148822685 TOP3A Chr17:18177347 T/C
rs143447104 TOP3A Chr17:18177493 C/T
rs184399818 TOP3A Chr17:18177566 A/C
rs3088175 TOP3A Chr17:18177578 T/G
rs17732686 TOP3A Chr17:18177661 C/T
rs1925 TOP3A Chr17:18177715 G/A
rs115214429 TOP3A Chr17:18177733 G/C
rs147996657 TOP3A Chr17:18177757 G/A
rs11555081 TOP3A Chr17:18177945 C/G
rs72535836 TOP3A Chr17:18178012 -/G
rs3215557 TOP3A Chr17:18178013 -/G
rs33964928 TOP3A Chr17:18178014 -/G
rs189340852 TOP3A Chr17:18178027 A/G
Total:2 Current:1  [First] [Prev] Next Last 
miRNA:

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Records:37
Gene Gen_transcript miRNA miR_location
TOP3A ENST00000360058 hsa-mir-106a-5p ChrX:133304274-133304296[-]
TOP3A ENST00000360058 hsa-mir-106b-5p Chr7:99691666-99691686[-]
TOP3A ENST00000360058 hsa-mir-133a Chr18:19405673-19405694[-]
TOP3A ENST00000360058 hsa-mir-133a Chr20:61162177-61162198[+]
TOP3A ENST00000360058 hsa-mir-133b Chr6:52013786-52013807[+]
TOP3A ENST00000360058 hsa-mir-141-5p Chr12:7073276-7073297[+]
TOP3A ENST00000360058 hsa-mir-17-5p Chr13:92002872-92002894[+]
TOP3A ENST00000360058 hsa-mir-200a-5p Chr1:1103258-1103279[+]
TOP3A ENST00000360058 hsa-mir-20a-5p Chr13:92003326-92003348[+]
TOP3A ENST00000360058 hsa-mir-20b-5p ChrX:133303880-133303902[-]
TOP3A ENST00000360058 hsa-mir-25-5p Chr7:99691233-99691253[-]
TOP3A ENST00000360058 hsa-mir-28-3p Chr3:188406622-188406643[+]
TOP3A ENST00000360058 hsa-mir-299-5p Chr14:101490137-101490158[+]
TOP3A ENST00000360058 hsa-mir-323a-3p Chr14:101492119-101492139[+]
TOP3A ENST00000360058 hsa-mir-324-3p Chr17:7126627-7126646[-]
Total:3 Current:1  [First] [Prev] Next Last