Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

TOP3A

Description:

topoisomerase (DNA) III alpha [Source:HGNC Symbol;Acc:11992]

Location:

Chr17:18174742-18218321[-]

CRmiRSNP:

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Records:null

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1 [First] [Prev] [Next] [Last]

Compound:

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Records:390

Gene	Compound	Gen_sig	Exp_pattern
TOP3A	NSC 704286	0.027	Down
TOP3A	NSC 704430	0.001	Up
TOP3A	NSC 704556	0.024	Down
TOP3A	NSC 704598	0.021	Up
TOP3A	NSC 705158	0.04	Down
TOP3A	NSC 707083	0.02	Up
TOP3A	2-Butenoic acid, 4-[[4,5-dichloro-2-[[[[2-(1-pyrrolidinyl)cyclohexyl] (methyl)amino]carbonyl]methyl]phenyl]amino]-4-oxo-, methyl ester, (1S,2S)-	0.002	Down
TOP3A	NSC 708044	0.02	Down
TOP3A	Piperazine-2,2,5,5-tetracarbonitrile, 3,6-dipropyl-	0.027	Down
TOP3A	NSC 708089	0.024	Down
TOP3A	NSC 708127	0.002	Down
TOP3A	NSC 708416	0.008	Down
TOP3A	3-Iodoacetamido-benzoylurea	0.005	Down
TOP3A	NSC 708446	0.016	Down
TOP3A	NSC 709151	0.009	Down

Expression pattern: Sensitivity / Resistance
Total:26 Current:20 First Prev Next Last

SNP:

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Records:17

SNP	Gene	SNP_location	SNP_allele
rs181367694	TOP3A	Chr17:18177270	A/G
rs117810073	TOP3A	Chr17:18177312	G/A
rs148822685	TOP3A	Chr17:18177347	T/C
rs143447104	TOP3A	Chr17:18177493	C/T
rs184399818	TOP3A	Chr17:18177566	A/C
rs3088175	TOP3A	Chr17:18177578	T/G
rs17732686	TOP3A	Chr17:18177661	C/T
rs1925	TOP3A	Chr17:18177715	G/A
rs115214429	TOP3A	Chr17:18177733	G/C
rs147996657	TOP3A	Chr17:18177757	G/A
rs11555081	TOP3A	Chr17:18177945	C/G
rs72535836	TOP3A	Chr17:18178012	-/G
rs3215557	TOP3A	Chr17:18178013	-/G
rs33964928	TOP3A	Chr17:18178014	-/G
rs189340852	TOP3A	Chr17:18178027	A/G

Total:2 Current:1 [First] [Prev] Next Last

miRNA:

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Records:37

Gene	Gen_transcript	miRNA	miR_location
TOP3A	ENST00000360058	hsa-mir-106a-5p	ChrX:133304274-133304296[-]
TOP3A	ENST00000360058	hsa-mir-106b-5p	Chr7:99691666-99691686[-]
TOP3A	ENST00000360058	hsa-mir-133a	Chr18:19405673-19405694[-]
TOP3A	ENST00000360058	hsa-mir-133a	Chr20:61162177-61162198[+]
TOP3A	ENST00000360058	hsa-mir-133b	Chr6:52013786-52013807[+]
TOP3A	ENST00000360058	hsa-mir-141-5p	Chr12:7073276-7073297[+]
TOP3A	ENST00000360058	hsa-mir-17-5p	Chr13:92002872-92002894[+]
TOP3A	ENST00000360058	hsa-mir-200a-5p	Chr1:1103258-1103279[+]
TOP3A	ENST00000360058	hsa-mir-20a-5p	Chr13:92003326-92003348[+]
TOP3A	ENST00000360058	hsa-mir-20b-5p	ChrX:133303880-133303902[-]
TOP3A	ENST00000360058	hsa-mir-25-5p	Chr7:99691233-99691253[-]
TOP3A	ENST00000360058	hsa-mir-28-3p	Chr3:188406622-188406643[+]
TOP3A	ENST00000360058	hsa-mir-299-5p	Chr14:101490137-101490158[+]
TOP3A	ENST00000360058	hsa-mir-323a-3p	Chr14:101492119-101492139[+]
TOP3A	ENST00000360058	hsa-mir-324-3p	Chr17:7126627-7126646[-]

Total:3 Current:1 [First] [Prev] Next Last