Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

PKN2

Description:

protein kinase N2 [Source:HGNC Symbol;Acc:9406]

Location:

Chr1:89149905-89301938[+]

CRmiRSNP:

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Records:null

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1 [First] [Prev] [Next] [Last]

Compound:

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Records:323

Gene	Compound	Gen_sig	Exp_pattern
PKN2	1, 1'[Pentane-1,5-diyl)dioxy]bis(11as)-2-fluoro-7-methoxy-1,2,3 ,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one	0.014	Up
PKN2	Dasatinib	0.047	Down
PKN2	NSC 732719	0.008	Up
PKN2	NSC 734385	0.033	Up
PKN2	6-(3-Bromopropyl)-5,6-dihydro-9-methyl-3-nitro-5,11-dioxo-11 H-indeno[1,2-c]isoquinoline	0.022	Up
PKN2	NSC 736188	0.041	Up
PKN2	6-(3-Aminopropyl)-5,6-dihyro-9-iodo-3-nitro-5,11-dioxo-11H-i ndeno[1,2-c]isoquinoline Hydrochloride	0.001	Up
PKN2	7-(2-Pyrrolidinoethyl)oximino-5-androsten-3b,17b-diol diacetate	0.014	Up
PKN2	6-(3-Chloropropyl)-5,6-dihydro-2,3,9-trimethoxy-5,11-dioxo-1 1H-indeno[1,2-c]isoquinoline	0.001	Up
PKN2	6-[3-[2-[1,2,4]-Triazolyl-1-propyl]-5,6-dihydro-2,3-dimethox y-8,9-methylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinolin e Hydrochloride	0.001	Up
PKN2	6-(3-Aminopropyl)-9-ethoxy-5,6-dihydro-3-nitro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline Hydrochloride	0.001	Up
PKN2	1-Acetyl-3-(4H-3,1-benzoxazin-2-yl)imidazolidin-2-thione	0.002	Up
PKN2	6-(3-fluoro-4-methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-2H-pyran-2-one	0.02	Up
PKN2	NSC 740986	0.004	Up
PKN2	12-Benzyl-5,12-dihydro-indeno[2',1':4,5]pyrrolo[3,2-c]chinolin-6,7-dione	0.011	Down

Expression pattern: Sensitivity / Resistance
Total:22 Current:20 First Prev Next Last

SNP:

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Records:46

SNP	Gene	SNP_location	SNP_allele
rs148906887	PKN2	Chr1:89299231	TTG/-
rs187904669	PKN2	Chr1:89299252	A/G
rs3831022	PKN2	Chr1:89299290	CTT/-
rs76669528	PKN2	Chr1:89299331	T/C
rs147551533	PKN2	Chr1:89299352	T/C
rs141963409	PKN2	Chr1:89299373	A/G
rs145835594	PKN2	Chr1:89299395	G/T
rs11541543	PKN2	Chr1:89299429	G/A
rs151165483	PKN2	Chr1:89299510	A/G
rs191409712	PKN2	Chr1:89299549	C/A
rs199950121	PKN2	Chr1:89299594	-/T
rs183934392	PKN2	Chr1:89299600	T/A
rs142129138	PKN2	Chr1:89299601	-/A
rs57445331	PKN2	Chr1:89299601	A/T
rs61703221	PKN2	Chr1:89299602	-/A

Total:4 Current:1 [First] [Prev] Next Last

miRNA:

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Records:82

Gene	Gen_transcript	miRNA	miR_location
PKN2	ENST00000370521	hsa-let-7d-3p	Chr9:96941177-96941198[+]
PKN2	ENST00000316005	hsa-mir-10a-3p	Chr17:46657226-46657247[-]
PKN2	ENST00000361935	hsa-mir-122-5p	Chr18:56118320-56118341[+]
PKN2	ENST00000361935	hsa-mir-130b-5p	Chr22:22007605-22007625[+]
PKN2	ENST00000316005	hsa-mir-135a-5p	Chr12:97957612-97957634[+]
PKN2	ENST00000316005	hsa-mir-135a-5p	Chr3:52328286-52328308[-]
PKN2	ENST00000316005	hsa-mir-135b-5p	Chr1:205417489-205417511[-]
PKN2	ENST00000361935	hsa-mir-135b-5p	Chr1:205417489-205417511[-]
PKN2	ENST00000316005	hsa-mir-137	Chr1:98511647-98511669[-]
PKN2	ENST00000316005	hsa-mir-138-2-3p	Chr16:56892486-56892507[+]
PKN2	ENST00000361935	hsa-mir-151a-3p	Chr8:141742686-141742706[-]
PKN2	ENST00000361935	hsa-mir-187-3p	Chr18:33484798-33484819[-]
PKN2	ENST00000361935	hsa-mir-191-5p	Chr3:49058105-49058127[-]
PKN2	ENST00000361935	hsa-mir-196a-3p	Chr12:54385583-54385604[+]
PKN2	ENST00000361935	hsa-mir-199a-5p	Chr19:10928145-10928167[-]

Total:6 Current:1 [First] [Prev] Next Last