Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

IRF8

Description:

interferon regulatory factor 8 [Source:HGNC Symbol;Acc:5358]

Location:

Chr16:85932409-85956197[+]

CRmiRSNP:

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Records:184

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type
NSC 291	rs1568391	1.36E-05	M2	IRF8	0.004	Target_3'utr
NSC 2805	rs1568391	0.000297619	M2	IRF8	0.013	Target_3'utr
NSC 4114	rs1568391	2.29E-05	M2	IRF8	0.003	Target_3'utr
NSC 16857	rs1568391	0.0178227	M2	IRF8	0.02	Target_3'utr
NSC 17757	rs1568391	0.000297619	M2	IRF8	0.023	Target_3'utr
NSC 25141	rs1568391	0.001029656	M2	IRF8	0.039	Target_3'utr
NSC 26040	rs1568391	0.001803415	M2	IRF8	0.025	Target_3'utr
NSC 27413	rs1568391	2.29E-05	M2	IRF8	0.021	Target_3'utr
NSC 29182	rs1568391	0.000115934	M2	IRF8	0.037	Target_3'utr
NSC 29638	rs1568391	0.000137541	M2	IRF8	0.044	Target_3'utr
NSC 41782	rs1568391	0.000245098	M2	IRF8	0.034	Target_3'utr
NSC 61811	rs1568391	0.01419169	M1	IRF8	0.011	Target_3'utr
NSC 61811	rs1568391	3.85E-05	M2	IRF8	0.011	Target_3'utr
NSC 74502	rs1568391	0.000125313	M2	IRF8	0.007	Target_3'utr
NSC 82181	rs1568391	0.00016231	M2	IRF8	0.009	Target_3'utr

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:13 Current:1 [First] [Prev] Next Last

Compound:

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Records:305

Gene	Compound	Gen_sig	Exp_pattern
IRF8	Ethyl 4-[6-(2-furyl)-2-(methylsulfanyl)-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-3-yl]butanoate	0.012	Up
IRF8	4-(4-Chloro-phenyl)-7a-methyl-2,5-diphenyl-7aH-cyclopenta[b] pyran-7-one	0.013	Down
IRF8	6-(3-Bromopropyl)-5,6-dihydro-9-methyl-3-nitro-5,11-dioxo-11 H-indeno[1,2-c]isoquinoline	0.041	Down
IRF8	4-[(Z)-2-(5-nitro-2-furyl)ethenyl]-6-(4-phenylpiperazin-1-yl )-1,3,5-triazin-2-ylamine	0.038	Down
IRF8	NSC 736151	0.035	Up
IRF8	1,2-Dithiolan-3-yl-N-(3'-methoxyestra-1',3',5'(10')-triene-1 7'b-yl)pentanamide	0.044	Down
IRF8	NSC 736188	0.028	Down
IRF8	6-(3-Aminopropyl)-5,6-dihyro-9-iodo-3-nitro-5,11-dioxo-11H-i ndeno[1,2-c]isoquinoline Hydrochloride	0.007	Down
IRF8	6-(3-Aminopropyl)-5,6-dihydro-3-nitro-5,11-dioxo-9-thiomethy l-11H-indeno[1,2-c]isoquinoline Hydrochloride	0.013	Down
IRF8	7-(2-Pyrrolidinoethyl)oximino-5-androsten-3b,17b-diol diacetate	0.045	Down
IRF8	6-(3-Aminopropyl)-5,6-dihbydro-3-nitro-5,11-dioxo-9-phenyl-1 1H[1,2-c]isoquinoline Hydrochloride	0.005	Down
IRF8	NSC 737745	0.01	Down
IRF8	(-)-dactylolide	0.03	Down
IRF8	6-(10'-tert-BOC-aminododecyl)-5,6-dihydro-5,11-dioxo-11H-indeno-[1,2-c]isoquinoline	0.01	Up
IRF8	5,6-Dihydro-6-[3-(2-hydroxyethyl)amino-1-propyl]-3-nitro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline Hydrochloride	0.003	Down

Expression pattern: Sensitivity / Resistance
Total:21 Current:19 First Prev Next Last

SNP:

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Records:70

SNP	Gene	SNP_location	SNP_allele
rs112869360	IRF8	Chr16:85954893	G/A
rs112869360	IRF8	ChrLRG_294:85954893	G/A
rs202085053	IRF8	Chr16:85954903	C/T
rs202085053	IRF8	ChrLRG_294:85954903	C/T
rs186737180	IRF8	Chr16:85954951	C/G
rs186737180	IRF8	ChrLRG_294:85954951	C/G
rs147732387	IRF8	Chr16:85955136	A/G
rs147732387	IRF8	ChrLRG_294:85955136	A/G
rs35039839	IRF8	Chr16:85955161	T/-
rs35039839	IRF8	ChrLRG_294:85955161	T/-
rs149189791	IRF8	Chr16:85955186	G/A
rs149189791	IRF8	ChrLRG_294:85955186	G/A
rs28368116	IRF8	Chr16:85955194	A/C
rs28368116	IRF8	ChrLRG_294:85955194	A/C
rs34845063	IRF8	Chr16:85955198	T/-

Total:5 Current:1 [First] [Prev] Next Last

miRNA:

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Records:16

Gene	Gen_transcript	miRNA	miR_location
IRF8	ENST00000268638	hsa-mir-150-5p	Chr19:50004089-50004110[-]
IRF8	ENST00000268638	hsa-mir-202-5p	Chr10:135061076-135061097[-]
IRF8	ENST00000268638	hsa-mir-31-3p	Chr9:21512120-21512141[-]
IRF8	ENST00000268638	hsa-mir-331-3p	Chr12:95702256-95702276[+]
IRF8	ENST00000268638	hsa-mir-365a-3p	Chr16:14403197-14403218[+]
IRF8	ENST00000268638	hsa-mir-373-3p	Chr19:54292002-54292024[+]
IRF8	ENST00000268638	hsa-mir-433	Chr14:101348286-101348307[+]
IRF8	ENST00000268638	hsa-mir-516b-5p	Chr19:54228711-54228732[+]
IRF8	ENST00000268638	hsa-mir-516b-5p	Chr19:54240114-54240135[+]
IRF8	ENST00000268638	hsa-mir-518a-3p	Chr19:54234310-54234331[+]
IRF8	ENST00000268638	hsa-mir-518a-3p	Chr19:54242639-54242660[+]
IRF8	ENST00000268638	hsa-mir-518d-5p	Chr19:54238146-54238167[+]
IRF8	ENST00000268638	hsa-mir-518f-3p	Chr19:54203321-54203341[+]
IRF8	ENST00000268638	hsa-mir-646	Chr20:58883592-58883610[+]
IRF8	ENST00000268638	hsa-mir-934	ChrX:135633051-135633072[+]

Total:2 Current:1 [First] [Prev] Next Last