Search_Gene

Query Gene
Gene name: Example: BCL2L11, ERCC1

Symbol:

TOP3A

Description:

topoisomerase (DNA) III alpha [Source:HGNC Symbol;Acc:11992]

Location:

Chr17:18174742-18218321[-]

CRmiRSNP:

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Records:null

Compound	CRmiRSNP	SNP_sig	Model	Molecule	Mol_sig	Type

Model : M1-Allele, M2-Recessive, M3-Additive, M4-Dominant
Total:0 Current:1 [First] [Prev] [Next] [Last]

Compound:

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Records:390

Gene	Compound	Gen_sig	Exp_pattern
TOP3A	Propanimidoyl chloride, N-[[[(3,4-dichlorophenyl)amino] carbonyl]oxy]-2-methyl-	0.007	Down
TOP3A	Propanimidoyl chloride, N-[[[(3-chloro-4-fluorophenyl) amino]carbonyl]oxy]-2-methyl-	0.015	Down
TOP3A	Propanimidoyl chloride, N-[[[(4-bromophenyl)amino] carbonyl]oxy]-2-methyl-	0.033	Down
TOP3A	Propanimidoyl chloride, 2-methyl- N-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]oxy]-	0.038	Down
TOP3A	Propanimidoyl chloride, 2-methyl-N-[[[[4-(methoxy- carbonyl)phenyl]amino]carbonyl]oxy]-	0.027	Down
TOP3A	Butanimidoyl chloride, N-[[[(3-fluorophenyl)amino] carbonyl]oxy]-	0.03	Down
TOP3A	Propanimidoyl chloride, N-[[[(4-methoxyphenyl)amino] carbonyl]oxy]-	0.035	Down
TOP3A	Boronic acid, [3-methyl-1-[[1-oxo-4-phenyl- 2-[[(2-quinolinyl)carbonyl]amino]butyl]amino]butyl]-	0.001	Down
TOP3A	NSC 683555	0.013	Down
TOP3A	NSC 684807	0.006	Down
TOP3A	NSC 684981	0.033	Up
TOP3A	NSC 684987	0.016	Up
TOP3A	NSC 685265	0.008	Down
TOP3A	NSC 685827	0.039	Down
TOP3A	4(3H)-Quinazolinone, 3-[[(2-nitrophenyl)methylene]amino]-2-phenyl-	0.021	Up

Expression pattern: Sensitivity / Resistance
Total:26 Current:15 First Prev Next Last

SNP:

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Records:17

SNP	Gene	SNP_location	SNP_allele
rs181367694	TOP3A	Chr17:18177270	A/G
rs117810073	TOP3A	Chr17:18177312	G/A
rs148822685	TOP3A	Chr17:18177347	T/C
rs143447104	TOP3A	Chr17:18177493	C/T
rs184399818	TOP3A	Chr17:18177566	A/C
rs3088175	TOP3A	Chr17:18177578	T/G
rs17732686	TOP3A	Chr17:18177661	C/T
rs1925	TOP3A	Chr17:18177715	G/A
rs115214429	TOP3A	Chr17:18177733	G/C
rs147996657	TOP3A	Chr17:18177757	G/A
rs11555081	TOP3A	Chr17:18177945	C/G
rs72535836	TOP3A	Chr17:18178012	-/G
rs3215557	TOP3A	Chr17:18178013	-/G
rs33964928	TOP3A	Chr17:18178014	-/G
rs189340852	TOP3A	Chr17:18178027	A/G

Total:2 Current:1 [First] [Prev] Next Last

miRNA:

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Records:37

Gene	Gen_transcript	miRNA	miR_location
TOP3A	ENST00000360058	hsa-mir-106a-5p	ChrX:133304274-133304296[-]
TOP3A	ENST00000360058	hsa-mir-106b-5p	Chr7:99691666-99691686[-]
TOP3A	ENST00000360058	hsa-mir-133a	Chr18:19405673-19405694[-]
TOP3A	ENST00000360058	hsa-mir-133a	Chr20:61162177-61162198[+]
TOP3A	ENST00000360058	hsa-mir-133b	Chr6:52013786-52013807[+]
TOP3A	ENST00000360058	hsa-mir-141-5p	Chr12:7073276-7073297[+]
TOP3A	ENST00000360058	hsa-mir-17-5p	Chr13:92002872-92002894[+]
TOP3A	ENST00000360058	hsa-mir-200a-5p	Chr1:1103258-1103279[+]
TOP3A	ENST00000360058	hsa-mir-20a-5p	Chr13:92003326-92003348[+]
TOP3A	ENST00000360058	hsa-mir-20b-5p	ChrX:133303880-133303902[-]
TOP3A	ENST00000360058	hsa-mir-25-5p	Chr7:99691233-99691253[-]
TOP3A	ENST00000360058	hsa-mir-28-3p	Chr3:188406622-188406643[+]
TOP3A	ENST00000360058	hsa-mir-299-5p	Chr14:101490137-101490158[+]
TOP3A	ENST00000360058	hsa-mir-323a-3p	Chr14:101492119-101492139[+]
TOP3A	ENST00000360058	hsa-mir-324-3p	Chr17:7126627-7126646[-]

Total:3 Current:1 [First] [Prev] Next Last