Characterizing chemoresponse communities at transcriptional and post-transcriptional levels.
The detailed records of NSC 678345 were elucidated in the following 4 sections: 1) Basis: basic information about NSC 678345; 2) Community: the network communities that were significantly associated with the response to NSC 678345; 3) Molecule: the relationships between components within communities and NSC 678345; 4) MDR: the compounds that were significantly associated with the NSC 678345.
| Molecule | Community | Type | Significance | SigClass |
|---|---|---|---|---|
| NR4A1 | Community19 | Gene | 0.15806979 | insignificant |
| POMC | Community19 | Gene | 0.20765 | insignificant |
| SMAD3 | Community27 | Gene | 0.10229621 | insignificant |
| TGFB2 | Community27 | Gene | 0.010745411 | significant |
| hsa-miR-200a-3p | Community27 | miRNA | 0.49314188 | insignificant |
| CCNA2 | Community36 | Gene | 0.081437683 | insignificant |
| HMGA2 | Community36 | Gene | 0.047001362 | significant |
| hsa-let-7b-5p | Community36 | miRNA | 0.22278492 | insignificant |