Characterizing chemoresponse communities at transcriptional and post-transcriptional levels.
The detailed records of NSC 645070 were elucidated in the following 4 sections: 1) Basis: basic information about NSC 645070; 2) Community: the network communities that were significantly associated with the response to NSC 645070; 3) Molecule: the relationships between components within communities and NSC 645070; 4) MDR: the compounds that were significantly associated with the NSC 645070.
| Molecule | Community | Type | Significance | SigClass |
|---|---|---|---|---|
| E2F2 | Community24 | Gene | 0.022710813 | significant |
| hsa-miR-24-3p | Community24 | miRNA | 0.14354086 | insignificant |
| SMAD3 | Community27 | Gene | 0.0061830978 | significant |
| TGFB2 | Community27 | Gene | 0.018295929 | significant |
| hsa-miR-200a-3p | Community27 | miRNA | 0.37940835 | insignificant |
| EGR1 | Community28 | Gene | 0.39582861 | insignificant |
| NFKB1 | Community28 | Gene | 0.010548907 | significant |
| hsa-miR-146b-5p | Community28 | miRNA | 0.24625336 | insignificant |